Alterations in CC fibers have been reported in PTSD and might be assumed to underlie substantial behavioral and cognitive sequelae however most diffusion tensor imaging (DTI) studies in adult-onset PTSD failed to address the clinical correlates between imaging and PTSD symptoms severity, behavioral manifestation and cognitive functions. The corpus callosum (CC) is the principal white-matter fiber bundle, crucial in relaying sensory, motor and cognitive information between hemispheres. Recently, white-matter tracts have become a focus of research in PTSD. Abstract Altered brain anatomy in specific gray-matter regions has been shown in patients with posttraumatic stress disorder (PTSD).
